- by Admin
- 2022-07-02 10:24:22 March
QUANTIFICATION OF PHYTOCHEMICAL AND METABOLOMICS PROFILING OF THE NIGERIANâ€™S BOTANICAL APHRODISIAC Microdesmis keayana (MICRODESMIS) J. LEONARD (PANDACEAE) ROOT
Microdesmis keayana is commonly known as microdesmis and is used in South-Western Nigeria as an aphrodisiac. Despite its extensive traditional usage, the bioactive constituents of this plant’s roots are yet to be explored thoroughly. The present study was carried out to actuate the chemical components of Microdesmis keayana root by quantitative phytochemical screening and gas chromatography-mass spectrometry (GC-MS). Sixty grams of the powdered roots was sequentially extracted by ethanol and later tested for preliminary quantitative phytochemical screening and further subject to GC-MS analysis. The results showed the presence of alkaloids (17.85±0.48), flavonoids (6.17±0.27), tannins (6.17±0.27), steroids (5.53±0.1), saponins (9.25±0.02), phenols (3.01±0.11) and cardiac glycoside (3.41±0.13) in the extract. The GC-MS analysis revealed the presence of 14 major compounds of different chemical class relevant to the National Institute of Standards and Technology (NIST) library. The findings indicated that the studied plant possesses therapeutic compounds that could improve a person’s health, and therefore justifies its traditional usage in the management of male sexual dysfunction and other reproductive disorders.